Jangham Jung, PhD

Jangham Jung studies cellular lineage and therapeutic response in brain tumors, including medulloblastoma. His Diaz Lab work combines functional studies with single-cell and spatial profiling.

Diaz Lab Publications

• Jain et al. Longitudinal single-cell and spatial profiling of sonic hedgehog medulloblastoma identifies novel therapeutic targets. Genome Medicine. Accepted. No DOI assigned.
• Okada et al. Single-nucleus profiling of postmortem diffuse midline gliomas identifies mitochondrial biogenesis as a resistance mechanism to imipridone therapy. Neuro Oncol. 2026.
• Kuwahara et al. AAV immuno-gene therapy platform delivering vectorized cytokines defines a new modality for high-grade glioma treatment. Mol Ther Oncol. 2026.
• Osorio et al. Developmental Plasticity and Stromal Co-option Shape a Pituitary Neuroendocrine Tumor Transcriptional Continuum. bioRxiv. 2025. [Preprint]
• Yu et al. Measles Oncolytic Virus as an Immunotherapy for Recurrent/Refractory Pediatric Medulloblastoma and Atypical Teratoid/Rhabdoid Tumor: Results from PNOC005. Clin Cancer Res. 2025.
• Kwok et al. Tumour-wide RNA splicing aberrations generate actionable public neoantigens. Nature. 2025.
• Lad et al. Glioblastoma induces the recruitment and differentiation of dendritic-like "hybrid" neutrophils from skull bone marrow. Cancer Cell. 2024.
• Wang et al. A single-cell atlas of glioblastoma evolution under therapy reveals cell-intrinsic and cell-extrinsic therapeutic targets. Nat Cancer. 2022.